Neurotoxic activity and ultrastructural changes in muscles caused by the brown widow spider Latrodectus geometricus venom

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Neurotoxic activity and ultrastructural changes in muscles caused by the brown widow spider Latrodectus geometricus venom.

Brown widow spider (Latrodectus geometricus) venom (BrWSV) produces few local lesions and intense systemic reactions such as cramps, harsh muscle pains, nausea, vomiting and hypertension. Approximately 16 protein bands under reducing conditions and approximately 14 bands under non-reducing conditions on a 12.5% sodium dodecyl sulfate-polyacrylamide gel electrophoresis were observed. Neurotoxic ...

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First record of a brown widow spider Latrodectus geometricus Koch, 1841 (Araneae, Theridiidae) feeding scorpion (Scorpiones, Bothriuridae) in a Brazilian Atlantic forest.

Scorpions are generalist predators, capturing a great variety of arthropods including even small vertebrates (Polis, 1990), however, they are also subject to predation, especially by vertebrates such as amphibians, reptiles, birds and mammals (Polis et al., 1981; McCormick and Polis, 1990). Regarding the invertebrates, there are reports of predation by coleopterans, chilopods, solpugids, others...

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Changes in the Fine Structure of the Neuromuscular Junction of the Frog Caused by Black Widow Spider Venom

Application of black widow spider venom to the neuromuscular junction of the frog causes an increase in the frequency of miniature end-plate potentials (min.e.p.p.) and a reduction in the number of synaptic vesicles in the nerve terminal. Shortly after the increase in min.e.p.p. frequency, the presynaptic membrane of the nerve terminal has either infolded or "lifted." Examination of these infol...

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The black widow spider genus Latrodectus (Araneae: Theridiidae): phylogeny, biogeography, and invasion history.

The spider genus Latrodectus includes the widely known black widows, notorious because of the extreme potency of their neurotoxic venom. The genus has a worldwide distribution and comprises 30 currently recognized species, the phylogenetic relationships of which were previously unknown. Several members of the genus are synanthropic, and are increasingly being detected in new localities, an occu...

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Molecular and mechanical properties of major ampullate silk of the black widow spider, Latrodectus hesperus.

Molecular and material properties of major ampullate silk were studied for the cobweb-building black widow spider Latrodectus hesperus. Material properties were measured by stretching the silk to breaking. The strength was 1.0 +/- 0.2 GPa, and the extensibility was 34 +/- 8%. The secondary structure of the major ampullate silk protein was studied using carbon-13 NMR spectroscopy. Alanine underg...

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ژورنال

عنوان ژورنال: Revista do Instituto de Medicina Tropical de São Paulo

سال: 2009

ISSN: 0036-4665

DOI: 10.1590/s0036-46652009000200007